Bridging the Gap: A Novel Method for Hemorrhage Control

There are six important vital structures in the neck providing aerodigestive, nervous, endocrine, and circulatory functions and they are minimally protected by the skeletal system unlike other areas of the body. This lack of protection in the neck not only contributes to physician angst during treatment, but also to the high mortality and complication rate when injury occurs. Airway compromise and exsanguination are both very high priorities and the time required to deal with one can be to the detriment of the other. Rapidly controlling hemorrhage provides the time required to establish a definitive airway without further blood loss of an already depleted intravascular volume.

Method for Hemorrhage Control
Method for Hemorrhage Control

Delays in establishing definitive control of the airway can make the task of subsequent airway control difficult or impossible because of hematoma formation or injury/resuscitation induced edema leading to subsequent catastrophic airway obstruction. The Western Trauma Association (WTA) Critical Decisions in Trauma recommends direct manual pressure (DMP) be used as a first line response to penetrating neck injury. However, this approach has been associated with a low efficacy rate due to re-bleeding and exsanguination prior to reaching definitive operative care.

Simulation for Innovation

In an effort to advance oncology clinical pathways to the next level, a novel partnership was developed between the department of Clinical Effectiveness (CE) and the Clinical Simulation Center at a Comprehensive Cancer Center.

Simulation for Innovation
Simulation for Innovation

The Clinical Effectiveness Department’s mission is to support the implementation of the best and most current evidence through developing, maintaining, and evaluating patient care management tools (practice algorithms, electronic ordering tools, and plans of care). All patient care management tools are developed using current evidence, and they are maintained, implemented and evaluated ensuring the utmost safety and quality. They align with national and regulatory bodies for cancer and clinical management measures as well as with national quality and clinical measures requirements.

Obesity Kills: Can Genetics Help in the Targeting of Obesity Prevention?

Obesity is becoming a worldwide epidemic and is a major public-health-threatening problem in most countries in the world. A recent paper in The Lancet involving 19.2 million participants broke the news by forecasting that, if the current trends of weight gain continue, by 2025, the global obesity (BMI>30) prevalence will reach 18% among men and surpass 21% among women (39% for all); severe obesity will exceed 6% among men and 9% among women (BMI>35, 15% for all).

Obesity
Obesity

Obesity means an excess accumulation of body fat tissue and is caused by a combination of excessive food intake, a lack of physical activity, and genetic susceptibility.Severe and morbid obesity are associated with highly elevated risks of adverse health outcomes, i.e., metabolic diseases (type 2 diabetes), higher morbidity and mortality for a variety of diseases as well as higher overall mortality. It has been estimated that overweight decreases an individual’s life expectancy by eight years.

Family Needs of Caregivers of Stroke Survivors

Stroke is presently turning into a major public health problem pushing cardiovascular disease at the back as a cause of mortality in developing countries, particularly in the Asian subcontinents. Based on current estimate approximately 1.8 million people are affected yearly by stroke; one third die and a similar proportion remain disabled. Increasing incidence of stroke in India demands swift action.

Family Needs of Caregivers of Stroke Survivors
Stroke Survivors

Stroke is a family disease and has the potential to affect the health and quality of life not only of the individuals but their family caregiver as well. After discharge approximately 80% of stroke survivors live in community, more than a third of whom are dependent on the informal caregivers. It is evidenced that, caregivers play a major role in long term well-being and stroke rehabilitation. The emphasis on stroke rehabilitation should shift from being patient focused to an approach focused on both the patients and their caregivers.

The Weak Link in Veterans’ Medical Care: An Expanded Role for Community Healthcare Providers

Eighty percent of military veterans receive most of their medical care from non-VA community providers. These providers do not identify them as veterans. The result is that service-related medical and psychological conditions are underdiagnosed, proper referrals are not made, and veterans do not receive services to which they are entitled. Community healthcare providers should know why and how to identify veterans and how to take a basic military health history.

Veterans' Medical Care
Veterans’ Medical Care

Few of my patients served in the military. False. The reason for this belief is that they don’t ask patients one simple question, “Have you or someone close to you (spouse, child, parent, partner) ever served in the military.” In 2014, nine percent of adults (16 percent of males) above the age of 18 years have served in the military.If my patient has a medical problem related to past military service, they would tell me. False. Most veterans will not offer this information unless you ask them. That is why the American Academy of Nursing has started an initiative, “Have You Ever Served?” It encourages veterans to tell providers and practitioners to ask their patients about military service.I can usually spot a military veteran by his or her appearance. False. Most veterans look like your other patients. They are not all amputees, psychologically disturbed, or wearing an “I am a Veteran” cap.

Thiopeptide Antibiotics act on both Host and Microbe to Deliver Double Punch on Mycobacterial Infection

Infectious diseases, the second leading cause of death worldwide, exert a grave threat to the public health. This situation is aggravating due to the progressively emerging microbial resistance and the lack of new drugs into the clinic. Mycobacterial infection has had its notorious name engraved on the Georgia Guidestones. For instance, human tuberculosis, which is mainly caused by Mycobacterium tuberculosis, causes approximately more than 1.5 million deaths each year. The stinky devil shows no regret in escalating its influence and evolves multidrug-resistant tuberculosis levering up the costs of corresponding treatment. It brooks no delay to search for effective drugs against.

Thiopeptide Antibiotics
Thiopeptide Antibiotics

Natural products remain a major source for antibiotic discovery and drug development; however, the accessibility and efficiency for chemical synthesis of these compounds, as well as the associated investigation into their mechanisms of action, often get choked by challenges arising from the structural complexity.

A Review on Obesity

According to the Faculty of Public Health, obesity is “an excess of body fat frequently resulting in a significant impairment of health and longevity”. The global cause of obesity spread over worldwide rapidly because it is the major risk factor of metabolic diseases such as hyperlipidemia, hypertension, osteoarthritis, dyslipidemia, type 2 diabetes DM, arteriosclerosis, nutritional deficiency, obstructive sleep apnoea, musculoskeletal complications, cancer and obesity also related to imbalance in the glucose and lipid metabolism in Insulin resistance. Orthopaedic problems in children are also linked to obesity.

Obesity
Obesity

Obesity develops when energy gain from foodstuff and drink consumption, including alcohol, is larger than energy needs of the body’s metabolism over a prolonged period, resulting in the build up of excess body fat. The percentage of body fat in women is higher than that of men it is about 25-30% in women and 15-20% in men.