Letters to the Editor: Cost of Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, which affects the rectum and colon and may have other extra-intestinal manifestations. This incurable disease, increasing over the past years, has an important economic impact for the Spanish National Healthcare System. However, little is known about the cost of UC patients, especially those indirect costs. In the publication entitled “Costs of ulcerative colitis from a societal perspective in a regional health care area in Spain: a database Study”, a detailed observational, longitudinal and retrospective study, the authors estimate the costs associated to the management of ulcerative colitis (UC) from a social perspective in a regional healthcare area in Spain.

Ulcerative Colitis
Ulcerative Colitis

Between January 2002 and May 2012, data of patients with diagnosis of UC from six primary care centers and one hospital were recorded. A total of 285 subjects older than 18 years, who had at least two clinical and resource use data recorded and had 12 complete months follow-up since the diagnosis were included in the study.

Advertisements

Late-Life Mental Health Disorders. Data from a Population-Based Study

A worldwide trend is the increasing population of older people, both in the absolute numbers and percentages. In spite of the population ageing, little research is dedicated to late-life mental health. Conversely, mental illnesses in older people are highly prevalent and costly. Besides being affected by life-long chronic psychiatric disturbances, older people might run into new (or newly diagnosed) mental disorders. They include neurodegenerative disorders leading to dementias, late-onset psychoses, and ‘common mental disorders’ such as depressive, adjustment and anxiety disorders.

Late-Life Mental Health Disorders
Late-Life Mental Health Disorders

A few peculiarities of late-life mental health disorders deserve some comments. First, at older ages, psychiatric diseases often co-occur with other adverse medical conditions and this worsens prognoses and strengths psychotropic drugs side-effects.

Letters to the Editor: Cost of Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, which affects the rectum and colon and may have other extra-intestinal manifestations. This incurable disease, increasing over the past years, has an important economic impact for the Spanish National Healthcare System. However, little is known about the cost of UC patients, especially those indirect costs. In the publication entitled “Costs of ulcerative colitis from a societal perspective in a regional health care area in Spain: a database Study”, a detailed observational, longitudinal and retrospective study, the authors estimate the costs associated to the management of ulcerative colitis (UC) from a social perspective in a regional healthcare area in Spain.

Ulcerative Colitis
Ulcerative Colitis

Between January 2002 and May 2012, data of patients with diagnosis of UC from six primary care centers and one hospital were recorded. A total of 285 subjects older than 18 years, who had at least two clinical and resource use data recorded and had 12 complete months follow-up since the diagnosis were included in the study.

Diagnosis of Lewy Body Disease Presenting as a Posterior Cortical Atrophy

Posterior Cortical Atrophy (PCA) or Benson’s syndrome is a rare progressive clinico-radiological entity, characterized by the clinical consequences of an atrophy of the primary visual cortex (occipital), as well as the dorsal (occipitoparietal, “where?”) and ventral (occipitotemporal, “what?”) visual streams (for a recent review, see Beh and coworkers). Problems start typically in the late sixth, early seventh decade, and patients present initially with–often vague-visual complaints due to disturbed high-order visual processes, in the absence of significant ophthalmological abnormalities. Most prominent features of PCA are elements of Balint’s syndrome (simultanagnosia, ocular apraxia and optic ataxia) and of Gerstmann’s syndrome (finger agnosia, right-left confusion, agraphia and acalculia), but also spatial disorientation, visual agnosia, alexia, anomia, apraxia, prosopagnosia, hemineglect or transcortical sensory aphasia.

Lewy Body DiseasePCA is often considered as an atypical form of Alzheimer’s disease (AD), since most cases present findings compatible with this diagnosis, either because of post-mortem evidence of plaques and tangles or of in vivo evidence of abnormal amyloid burden, as measured by amyloid positron emission tomography (PET) imaging or cerebrospinal fluid (CSF) biomarker analysis. However, in some cases, pathological studies have found alternative diagnoses, such a prion diseases, corticobasal degeneration (CBD), subcortical gliosis or Lewy body disease (LBD).