A wide occurrence of genetic variations is seen in gene pool of every organism. These variations are found to be linked with cancer, turner syndrome, cystic fibrosis, etc. However, some of the variations have been proved to be beneficial in specific cases such as lowering of cholesterol level, increasing bone density, and developing of resistance for malaria. Hence, author concludes that genetic variations or switches can be explored for their noteworthy role in evolution of human species and pave a way for scientists to discover various therapeutic approaches.
Genetic variants can be either polygenic or monogenic depending on the number of genes involved. Monogenic mutations include single gene causing diseases which are considered as rare and severe diseases. These kinds of diseases run in families and are not adversely affected by environmental factors.