Cardiovascular Diseases on Latin-American People

It has been estimated that mortality from cardiovascular diseases (CVD) are almost three times more frequent in undeveloped Latin- American (LA) countries that developed countries, and because there were not enough publish data regarding the difference in risk profile of the LA vs. non LA population, the investigators of the CRUCIAL Study planned a sub analysis that could compare the behavior of the proactive interventional strategy in Latin-American vs. Non Latin American countries, as well the differences in the risk profile of the Latin American subjects compare with the rest of the world population included in the study.

Cardiovascular Diseases
Cardiovascular Diseases

It is also important to remember that the real worldwide behavior of the physicians was to treat Hypertension and Dyslipidemia as separate entities instead to treat cardiovascular risk. And hence The ASCOT Trial in the lipid lowering arm shown a clear benefit in relative risk reduction in mobility and mortality we pretend to address the question trough the design of the CRUCIAL Study to compare in real life the relative reduction in calculated Framingham coronary heart disease risk when a multiple risk factor intervention strategy, based on single-pill amlodipine besylate/atorvastatin calcium was compared with usual care strategy in patients with hypertension and > 3 additional cardiovascular risk factors and base line cholesterol < 6.5 mmol/L and no coronary heart disease.


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