Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS) with unpredictable course and a changeable, interindividually varying complex of symptoms with a lifelong progression which may result in disability. Since the disease is so far incurable, proper symptomatic treatment is very important in its management in addition to the disease modifying treatments.
Pain in MS is a very common symptom, with prevalence in patients ranging from 29 to 92%. The existing research has proven pain is a key problem in patients with MS. Svendsen et al. found that pain in MS patients was reported by similar proportions of MS patients and sex and age- stratified group from the general population, however pain intensity, the need for analgetic treatment and pain interference with activities of daily living were much higher in MS patients.