Review of the Etiological Causes and Diagnosis of Myelitis and Its Medical Orientation Protocol

Transverse myelitis covers heterogeneous inflammatory conditions of the spinal cord which can have devastating neurologic effects such as motor, sensory, and autonomic dysfunctions.It is imperative to note that myelopathy does not have the same meaning as myelitis, despite both terms imply spinal cord compromise due to a pathological event. On one hand, myelopathy can be caused by a range of etiologies. On the other hand, myelitis is referred to any spinal cord inflammatory event awaiting further classification after the identification of the cause. Another key reminder is that TM is currently used as a synonym to acute transverse myelitis in the literature.

Transverse myelitis
Transverse myelitis

For many years, an exact definition of TM or acute transverse myelitis (ATM) has been tried to be settled. The term “acute” varies depending on authors: Berman et al defined as more than 48 h, Tranverse Myelitis Consortium Working Group between 4 h and 21 days following the onset of symptoms and Jeffery et al. as maximal aggravation in 24 h.


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