Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells and oncology is a branch of medicine that deals with tumors. This review presents the current state of our knowledge of biomarkers in the selected oncology research area of lipomas (benign) and liposarcomas, (malign). A lipoma is a benign tumor composed of adipose tissue (body fat). It is the most common benign form of soft tissue tumor about 1 in 100 people (1%) will develop a lipoma.
Numerous case reports document the presence of lipomas in other, rare locations, with these tumors having been found virtually everywhere in the body. Although it has been hypothesized that lipomas may rarely undergo sarcomatous change, this event has never been convincingly documented. It is more probable that lipomas are at the benign end of the spectrum of tumors, which, at the malignant end, include liposarcomas (LS). Liposarcomas are a heterogeneous group of adipocytic tumors that represent approximately 13% of all sarcomas