Brucellosis is a rare multisystemic zoonotic infection caused by coccobacilli gram negative bacteria “brucella”. It is specially observed in endemic countries particularly in rural areas. Myalgia, arthralgia, fiver and asthenia are the main clinical manifestations. Neurological complications are rare reported in 3-5% of cases and affected both central and peripheral nervous system.
The most frequent neurological manifestations are meningitis and meningo-encephalitis. The other major complications in neurobrucellosis are neuropsychiatric symptoms (agitation, depression, confusion…), sleep disorder, epilepsy, headache, intracranial hypertension, cranial nerve (CN) involvement, and polyradiculoneuritis. However, thrombotic or hemorrhagic vascular complications are exceptional. Only few cases of cerebral venous thrombosis (CVT) due to neurobrucellosis were reported in literature.